O15393 | TMPS2_HUMAN | Transmembrane protease serine 2 (TMPRSS2)
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00089 | Trypsin - Trypsin | 256~484 | |
PF15494 | SRCR_2 - Scavenger receptor cysteine-rich domain | 153~247 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL3219087 | Ki | = | 1.0 | nM | 593.75 | COc1ccc(-c2cccc(S(=O)(=O)N[C@@H](Cc3cccc(C(=N)N)c3)C(=O)N3CCC(CCN)CC3)c2)c(OC)c1 | Homo sapiens | CHEMBL5216080 | assay format | |
CHEMBL1229259 | Ki | = | 20.0 | nM | 556.69 | N=C(N)NCCC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(C(=N)N)cc1 | Homo sapiens | CHEMBL1810435 | assay format | |
CHEMBL1809250 | Ki | = | 53.0 | nM | 501.66 | CCC(NCc1ccc(C(=N)N)cc1)C(=O)[C@@H](CCCNC(=N)N)NS(=O)(=O)Cc1ccccc1 | Homo sapiens | CHEMBL1810435 | assay format | |
CHEMBL1809251 | Ki | = | 68.0 | nM | 515.68 | CCC[C@H](NCc1ccc(C(=N)N)cc1)C(=O)[C@@H](CCCNC(=N)N)NS(=O)(=O)Cc1ccccc1 | Homo sapiens | CHEMBL1810435 | assay format |