3D structures mapped by conservation among orthologs

[ Domain: "C2 domain" // ANAPC8 ]

 PyMOL session

[ Domain: "C2 domain" // UNK_F_TYPE ]

 PyMOL session

[ Domain: "SAM domain-like" // SAM_1 ]

 PyMOL session

[ Domain: "SH2" // SH2 ]

 PyMOL session

[ Domain: "DNase I-like" // Exo_endo_phos ]

 PyMOL session

 [ Alpha Fold Model ] (go)

 Known binders annotated in ChEMBL

 IC50 CSV    Ki CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL5081948		IC50	=	61.0	nM	574.1	O=P(O)(O)Oc1cc(F)c(-c2cc(OP(=O)(O)O)c(OP(=O)(O)O)cc2F)cc1OP(=O)(O)O	Homo sapiens	CHEMBL5053561	single protein format
CHEMBL2337806		IC50	=	620.0	nM	371.89	C[C@H](NC(=O)c1sccc1OCc1ccc(Cl)cc1)c1ccccc1	Homo sapiens	CHEMBL2343088	single protein format
CHEMBL2337806		Ki	=	440.0	nM	371.89	C[C@H](NC(=O)c1sccc1OCc1ccc(Cl)cc1)c1ccccc1	Homo sapiens	CHEMBL5053566	assay format
CHEMBL4282693		Ki	=	440.0	nM	428.29	O=C(NCc1c(F)cccc1F)c1sccc1OCc1ccc(Cl)cc1Cl	Homo sapiens	CHEMBL5053566	assay format