O15120 | PLCB_HUMAN | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01553 | Acyltransferase - Acyltransferase | 77~205 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL34896 |  |
IC50 | = | 6.0 | nM | 377.25 | C#CCOC(=O)Nc1ccc(Cl)c(-c2nc3cc(Cl)ccc3s2)c1 | Homo sapiens | CHEMBL710871 | cell-based format |
| CHEMBL5219455 |  |
IC50 | = | 8.4 | nM | 345.41 | CCc1c(-c2nc(N)nc(Nc3ccc(C)cc3)n2)oc2ccccc12 | Homo sapiens | CHEMBL5216583 | cell-based format |
| CHEMBL75167 |  |
IC50 | = | 10.0 | nM | 385.81 | CCOc1ccc(Cl)cc1-c1cc(Nc2ccc([N+](=O)[O-])cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL35388 |  |
IC50 | = | 15.0 | nM | 410.8 | C#CCOC(=O)Nc1ccc(Cl)c(-c2nc3cc(C(F)(F)F)ccc3s2)c1 | Homo sapiens | CHEMBL710871 | cell-based format |
| CHEMBL35508 |  |
IC50 | = | 15.0 | nM | 356.83 | C#CCOC(=O)Nc1ccc(C)c(-c2nc3cc(Cl)ccc3s2)c1 | Homo sapiens | CHEMBL710871 | cell-based format |
| CHEMBL5219496 |  |
IC50 | = | 15.0 | nM | 345.41 | CCc1ccc(Nc2nc(N)nc(-c3oc4ccccc4c3C)n2)cc1 | Homo sapiens | CHEMBL5216583 | cell-based format |
| CHEMBL286394 |  |
IC50 | = | 15.0 | nM | 362.24 | N#CCC(=O)Nc1ccc(Cl)c(-c2nc3cc(Cl)ccc3s2)c1 | Homo sapiens | CHEMBL710871 | cell-based format |
| CHEMBL310136 |  |
IC50 | = | 16.0 | nM | 419.71 | CCOc1ccc(Br)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL77883 |  |
IC50 | = | 17.0 | nM | 410.28 | CCOc1ccc(Br)cc1-c1cc(Nc2ccc(C#N)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL308945 |  |
IC50 | = | 17.0 | nM | 375.26 | CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL74548 |  |
IC50 | = | 18.0 | nM | 434.14 | Cc1ccc(Br)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL307716 |  |
IC50 | = | 20.0 | nM | 365.65 | Nc1nc(Nc2ccc(Cl)cc2)cc(-c2cc(Cl)ccc2Cl)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL311379 |  |
IC50 | = | 22.0 | nM | 345.23 | Cc1ccc(Cl)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL74492 |  |
IC50 | = | 24.0 | nM | 380.84 | CCOc1ccc(Cl)cc1-c1cc(Nc2ccc3c[nH]nc3c2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL422579 |  |
IC50 | = | 27.0 | nM | 346.17 | N#CCC(=O)Nc1ccc(Cl)c(-c2nc3cc(Cl)ccc3o2)c1 | Homo sapiens | CHEMBL710871 | cell-based format |
| CHEMBL74708 |  |
IC50 | = | 28.0 | nM | 384.87 | CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CCO)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL424605 |  |
IC50 | = | 28.0 | nM | 405.68 | COc1ccc(Cl)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL74549 |  |
IC50 | = | 31.0 | nM | 389.68 | Cc1ccc(Br)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL72618 |  |
IC50 | = | 34.0 | nM | 427.3 | CCOc1ccc(Br)cc1-c1cc(Nc2ccc(C(C)=O)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |
| CHEMBL73376 |  |
IC50 | = | 34.0 | nM | 389.68 | Cc1ccc(Cl)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1 | Homo sapiens | CHEMBL710870 | cell-based format |