O15118 | NPC1_HUMAN | NPC intracellular cholesterol transporter 1 (NPC1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF12349 | Sterol-sensing | 650–802 | |
| PF16414 | NPC1_N | 23–266 | |
| PF22314 | NPC1_MLD | 392–607 |
3D structures mapped by conservation among orthologs
[ Domain: "Multidrug efflux transporter AcrB transmembrane domain" // Patched ]
[ Domain: "Multidrug efflux transporter AcrB transmembrane domain" // Sterol-sensing ]
[ Domain: "Multidrug efflux transporter AcrB pore domain" // ABC_transp_aux ]
[ Domain: "Multidrug efflux transporter AcrB pore domain" // 2A060601 ]
[ Domain: "Frizzled cysteine-rich domain-related" // NPC1_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|