O14986 | PI51B_HUMAN | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1B)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01504 | PIP5K | 110–393 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5171272 |  |
IC50 | = | 13.0 | nM | 430.51 | CNC(=O)c1cc(Nc2ccccc2)cc(-c2ccnc(NC(=O)C3CCOCC3)c2)c1 | Homo sapiens | CHEMBL5144918 | single protein format |
| CHEMBL5191668 |  |
IC50 | = | 35.0 | nM | 430.51 | CC(=O)Nc1cc(Nc2ccccc2)cc(-c2ccnc(NC(=O)C3CCOCC3)c2)c1 | Homo sapiens | CHEMBL5144918 | single protein format |
| CHEMBL5206569 |  |
IC50 | = | 46.0 | nM | 472.55 | CN(CC1OCCO1)C(=O)c1cc(Nc2ccccc2)cc(-c2ccnc(NC(=O)C3CC3)c2)c1 | Homo sapiens | CHEMBL5144918 | single protein format |
| CHEMBL203535 |  |
IC50 | = | 1000.0 | nM | 360.42 | O=C(Nc1cc(-c2ccnc(Nc3ccccc3)c2)ccn1)C1CCOC1 | Homo sapiens | CHEMBL5144918 | single protein format |