O14791 | APOL1_HUMAN | Apolipoprotein L1 (APOL1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF05461 | ApoL - Apolipoprotein L | 88~386 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5073628 |  |
IC50 | = | 0.25 | nM | 417.43 | NC(=O)C(CO)NCC1CC(c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc23)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5092759 |  |
IC50 | = | 0.25 | nM | 416.44 | CC(C)(CO)NC(=O)[C@H]1C[C@@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5089581 |  |
IC50 | = | 0.25 | nM | 432.44 | CC(CO)(CO)NC(=O)[C@H]1C[C@@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5087679 |  |
IC50 | = | 0.25 | nM | 428.45 | O=C(NC1(CO)CCC1)[C@H]1C[C@@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5091263 |  |
IC50 | = | 0.25 | nM | 408.37 | O=C(NCC(F)F)[C@H]1C[C@@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5081802 |  |
IC50 | = | 0.25 | nM | 388.39 | O=C(NCCO)[C@H]1C[C@@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5094728 |  |
IC50 | = | 0.25 | nM | 444.45 | O=C([C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1)N1CCOC[C@@H]1CO | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5079543 |  |
IC50 | = | 0.25 | nM | 428.45 | CC1(CO)CCN1C(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5076370 |  |
IC50 | = | 0.25 | nM | 414.43 | O=C([C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1)N1CC[C@H]1CO | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5080173 |  |
IC50 | = | 0.25 | nM | 416.44 | CC[C@@H](CO)NC(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5080687 |  |
IC50 | = | 0.25 | nM | 416.44 | CCC(CO)NC(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5088072 |  |
IC50 | = | 0.25 | nM | 464.43 | O=C(NC1(CO)CC(F)(F)C1)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5084737 |  |
IC50 | = | 0.25 | nM | 428.45 | O=C(NC(CO)C1CC1)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5092967 |  |
IC50 | = | 0.25 | nM | 439.44 | Cn1ncc(CNC(=O)[C@H]2C[C@H](c3c(-c4ccc(F)cc4)[nH]c4c(F)cc(F)cc43)C2)n1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5089445 |  |
IC50 | = | 0.25 | nM | 441.45 | CC1(NC(=O)[C@H]2C[C@H](c3c(-c4ccc(F)cc4)[nH]c4c(F)cc(F)cc43)C2)CCNC1=O | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5089805 |  |
IC50 | = | 0.25 | nM | 412.41 | C#CC(CO)NC(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5083679 |  |
IC50 | = | 0.25 | nM | 416.44 | CC(CO)N(C)C(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5076966 |  |
IC50 | = | 0.25 | nM | 428.45 | O=C([C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1)N1CCC[C@@H]1CO | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5088084 |  |
IC50 | = | 0.25 | nM | 427.43 | CC(C#N)(CO)NC(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |
| CHEMBL5085628 |  |
IC50 | = | 0.25 | nM | 428.41 | O=C1OCC[C@@H]1NC(=O)[C@H]1C[C@H](c2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc32)C1 | Homo sapiens | CHEMBL5053464 | cell-based format |