O14727 | APAF_HUMAN | Apoptotic protease-activating factor 1 (APAF1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00400 | WD40 | 611–642 | |
| PF00400 | WD40 | 648–685 | |
| PF00400 | WD40 | 689–729 | |
| PF00400 | WD40 | 734–771 | |
| PF00400 | WD40 | 875–909 | |
| PF00400 | WD40 | 1001–1031 | |
| PF00400 | WD40 | 1040–1071 | |
| PF00400 | WD40 | 1079–1113 | |
| PF00400 | WD40 | 1119–1155 | |
| PF00400 | WD40 | 1176–1203 | |
| PF00619 | CARD | 6–89 | |
| PF00931 | NB-ARC | 130–374 | |
| PF17908 | APAF1_C | 453–587 | |
| PF21296 | APAF-1-like_WHD | 378–445 |
3D structures mapped by conservation among orthologs
[ Domain: "7-bladed" // ANAPC4_WD40_10 ]
[ Domain: "8-bladed" // ANAPC4_WD40_10 ]
[ Domain: "winged" // KOG4658_like ]
[ Domain: "DEATH domain" // CARD ]
[ Domain: "AAA+ ATPase lid domain" // NB-ARC_2nd ]
[ Domain: "Apoptotic protease-activating factor 1 (Apaf-1) helical domain" // EUF08240 ]
[ Domain: "P-loop containing nucleoside triphosphate hydrolases" // NB-ARC_1st ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|