O00625 | PIR_HUMAN | Pirin (PIR)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02678 | Pirin - Pirin | 22~118 | |
| PF05726 | Pirin_C - Pirin C-terminal cupin domain | 171~277 |
3D structures mapped by conservation among orthologs
[ Domain: "Double-stranded beta-helix" // Pirin ]
[ Domain: "Double-stranded beta-helix" // Pirin_C ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4087666 |  |
IC50 | = | 33.0 | nM | 552.63 | Cc1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1NC(=O)c1ccc2nc(OCCN3CCCC3)ccc2c1 | Homo sapiens | CHEMBL4329880 | single protein format |
| CHEMBL4070633 |  |
IC50 | = | 44.0 | nM | 453.5 | Cc1ccc2cc(C(=O)Nc3cc(NC(=O)c4ccc5c(c4)OCCO5)ccc3C)ccc2n1 | Homo sapiens | CHEMBL4329880 | single protein format |
| CHEMBL1230020 |  |
IC50 | = | 670.0 | nM | 413.83 | CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F | Homo sapiens | CHEMBL4329880 | single protein format |