O00459 | P85B_HUMAN | Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00017 | SH2 | 330–405 | |
| PF00017 | SH2 | 622–696 | |
| PF00620 | RhoGAP | 125–258 | |
| PF16454 | PI3K_P85_iSH2 | 428–596 |
3D structures mapped by conservation among orthologs
[ Domain: "SH3" // SH3_1 ]
[ Domain: "GTPase activation domain, GAP" // RhoGAP ]
[ Domain: "Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain" // PI3K_P85_iSH2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4434674 |  |
IC50 | = | 630.0 | nM | 512.59 | COc1ncc(-c2cc(-c3ncc(CN4C[C@@H](C)O[C@@H](C)C4)o3)c3cn[nH]c3c2)cc1NS(C)(=O)=O | Homo sapiens | CHEMBL5150299 | single protein format |