O00400 | ACATN_HUMAN | Acetyl-coenzyme A transporter 1 (SLC33A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13000 | Acatn - Acetyl-coenzyme A transporter 1 | 75~285 | |
| PF13000 | Acatn - Acetyl-coenzyme A transporter 1 | 286~545 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3648555 |  |
IC50 | = | 0.8 | nM | 544.59 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n([C@H]2CC[C@H](O)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648538 |  |
IC50 | = | 0.9 | nM | 558.61 | CCCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n(C2CCOCC2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648544 |  |
IC50 | = | 1.0 | nM | 540.62 | CCCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCC(O)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648553 |  |
IC50 | = | 1.0 | nM | 570.65 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n([C@H]2CC[C@H](OCCO)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648629 |  |
IC50 | = | 1.2 | nM | 568.68 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCC(C(C)(C)O)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648554 |  |
IC50 | = | 1.3 | nM | 544.59 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n([C@H]2CC[C@@H](O)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648541 |  |
IC50 | = | 1.3 | nM | 554.65 | CCCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n([C@@H]2C[C@@H](C)O[C@@H](C)C2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648511 |  |
IC50 | = | 1.3 | nM | 512.61 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(CC(C)(C)C)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648539 |  |
IC50 | = | 1.3 | nM | 572.64 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n(C2CCOC(C)(C)C2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648537 |  |
IC50 | = | 1.3 | nM | 554.65 | CCCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCOC(C)(C)C2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648532 |  |
IC50 | = | 1.3 | nM | 530.56 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n(C2CCOCC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648551 |  |
IC50 | = | 1.3 | nM | 540.62 | CCCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCOC(C)C2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648540 |  |
IC50 | = | 1.4 | nM | 568.68 | CCCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCOC(C)(C)C2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648546 |  |
IC50 | = | 1.4 | nM | 566.66 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n([C@H]2CC[C@]3(CCCO3)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648543 |  |
IC50 | = | 1.4 | nM | 540.62 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCC(C)OC2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648557 |  |
IC50 | = | 1.4 | nM | 592.66 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n([C@H]2CC[C@H](c3nc(C)no3)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648522 |  |
IC50 | = | 1.4 | nM | 510.6 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(CC2(C)CC2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648556 |  |
IC50 | = | 1.4 | nM | 582.66 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n([C@H]2CC[C@H](C(=O)OCC)CC2)c2ncnn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648530 |  |
IC50 | = | 1.5 | nM | 560.66 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n(C2CCSCC2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |
| CHEMBL3648528 |  |
IC50 | = | 1.5 | nM | 544.59 | CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n(C2CCOCC2)c2nc(C)nn12 | Homo sapiens | CHEMBL3705164 | cell membrane format |