O00222 | GRM8_HUMAN | Metabotropic glutamate receptor 8 (GRM8)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF000037tm_3577–837
PF01094ANF_receptor75–477
PF07562NCD3G512–562

 3D structures mapped by conservation among orthologs

[ Domain: "Periplasmic binding protein-like I" // ANF_receptor_2nd_1 ]

 PyMOL session


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL285843 IC50 = 5.1 nM 183.1 NC(CCP(=O)(O)O)C(=O)O Homo sapiens CHEMBL828593 single protein format
CHEMBL575060 IC50 = 5.7 nM 147.13 N[C@@H](CCC(=O)O)C(=O)O Homo sapiens CHEMBL828593 single protein format