O00222 | GRM8_HUMAN | Metabotropic glutamate receptor 8 (GRM8)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00003 | 7tm_3 - 7 transmembrane sweet-taste receptor of 3 GCPR | 577~837 | |
| PF01094 | ANF_receptor - Receptor family ligand binding region | 75~477 | |
| PF07562 | NCD3G - Nine Cysteines Domain of family 3 GPCR | 512~562 |
3D structures mapped by conservation among orthologs
[ Domain: "Periplasmic binding protein-like I" // ANF_receptor_2nd_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL285843 |  |
IC50 | = | 5.1 | nM | 183.1 | NC(CCP(=O)(O)O)C(=O)O | Homo sapiens | CHEMBL828593 | single protein format |
| CHEMBL575060 |  |
IC50 | = | 5.7 | nM | 147.13 | N[C@@H](CCC(=O)O)C(=O)O | Homo sapiens | CHEMBL828593 | single protein format |