A0AVT1 | UBA6_HUMAN | Ubiquitin-like modifier-activating enzyme 6 (UBA6)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00899 | ThiF - ThiF family | 44~409 | |
| PF00899 | ThiF - ThiF family | 449~630 | |
| PF00899 | ThiF - ThiF family | 885~931 | |
| PF09358 | E1_UFD - Ubiquitin fold domain | 955~1042 | |
| PF10585 | UBA_E1_SCCH - Ubiquitin-activating enzyme, SCCH domain | 631~884 | |
| PF16190 | E1_FCCH - Ubiquitin-activating enzyme E1 FCCH domain | 225~292 | |
| PF16191 | E1_4HB - Ubiquitin-activating enzyme E1 four-helix bundle | 293~361 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2017005 |  |
IC50 | = | 920.0 | nM | 462.49 | NS(=O)(=O)OC[C@H]1O[C@@H](n2cnc3c(N[C@H]4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O | Homo sapiens | CHEMBL2328929 | single protein format |